Supermicro and AMD GenAI Solutions

Scaling GenAI from pilot to production requires data center ready infrastructure that balances power, cooling, and performance at rack scale. Supermicro servers with AMD EPYC™ processors and AMD Instinct™ MI325X accelerators deliver dense GPU capacity, ultra-fast throughput, and low latency for both training and inferencing. With advanced liquid cooling, multi-rack integration, and high-bandwidth networking, enterprises can maximize efficiency, reduce deployment risks, and future-proof their AI workloads for demanding real-world environments.

Optimized compute for GenAI Workloads

Supermicro servers featuring AMD EPYC processors deliver the high memory bandwidth, core density, and PCIe lanes required to support large-scale AI model training and inferencing.

Turnkey AI Infrastructure at Scale

Rack-level, liquid-cooled systems reduce deployment complexity while enabling efficient scaling from proof of concept to full production environments.

Validated GenAI Solution Stacks

Pre-integrated hardware and software stacks—including AMD ROCm™, PyTorch, and Kubernetes—accelerate time to value and streamline MLOps workflows.

Sustainability Meets Performance

Supermicro’s energy-efficient systems, combined with AMD’s power-optimized architecture, help reduce total cost of ownership and support sustainable AI operations.

Featured Products

8U GPU A+ Server

AS -8126GS-TNMR
DP AMD 8U System with AMD Instinct™ MI325X 8-GPU
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4U GPU A+ Server

AS -4126GS-NMR-LCC
DP AMD 4U Liquid-Cooled System with AMD Instinct™ MI355X 8-GPU (onsite service is required for liquid-cooling)
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4U GPU A+ Server

AS -4125GS-TNMR2-LCC
DP AMD 4U Liquid-Cooled System with AMD Instinct™ MI300X 8-GPU (onsite service is required for liquid-cooling)
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2U Hyper A+ Server

AS -2126HS-TN
2U Hyper with up to 24 hot-swap 2.5" NVMe/SAS/SATA bays and 4 PCIe 5.0 x16 slots + 1 PCIe 5.0 x16 AIOM slot
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5-Node MicroCloud

AS -3015MR-H5TNR
3U 5-Node MicroCloud with double-width GPU support
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4U GPU A+ Server

AS -4145GH-TNMR
4U System with Quad AMD Instinct™ MI300A Accelerators (onsite service OSNBD is required)
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5U GPU A+ Server

AS -5126GS-TNRT
DP AMD 5U System with 8 PCIe GPUs
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FlexTwin A+ Server

AS-2126FT-HE-LCC
2U 4-Node FlexTwin™ with liquid cooling (complete rack and onsite service are required)
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Successfully Moving Enterprise GenAI from Proof of Concept to Production

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